I have the My Buddy (the largest size) for my two - they are 9 and 11 lbs each - and they have plenty of room. I wanted them to be able to spread out and be comfortable during long car rides. I think with smaller pups the medium size would be okay for two. The only thing is I'm pretty sure it only comes with one seatbelt strap so you'd have to buy an additional one. I have had my Snoozer almost two years now and I absolutely love it. The dogs are comfortable and safe in the car and that makes going places much, much easier!