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Originally Posted by abbie's mom  Though this synthetic product may be used by some, with 'no problem', I have read many incidents where pups were taken to the vet and masses of these "bones" were found in tummies. I wouldn't waste money nor worry on synthetic chews. Rather, use natural bullysticks for chewing exercise. There are odorless bullysticks on this site, too. The Danger
If a dog chews off chunks larger than rice-size shavings, then a pet-owner should worry. Nylabone makers say chunks larger than a quarter of an inch may be harmful to a dog. If a dog swallows a quarter inch chunk or larger, owners should take the bone away and immediately consult a veterinarian. After all, Nylabone is made of synthetic polymers and is not meant for major ingestion.
I did see somewhere that Nylabone has edible products as well.
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With the Nylabone Dura Chews, chunks do not come off. As for that word "natural"...be careful because it does not equal safe all of the time.
Same thing for bully sticks! I have seen SO many cause GI issues...lots of YTers who swore by them, have stopped after having multiple bouts of diarrhea.
Choking and obstructions are also possible with bully sticks.
Bully Stick Dangers for Dogs | eHow.com
Bottom line: I do not EVER give my pups any edible chews. The only thing they need that is edible is food. Yes, I give treats, too...but even they are not necessary.