My dog Ralph almost had a reaction not for rabies but for some new type of shot that was made mandatory for my state, they said i did not need to give him the bendrly before so I did not. The next day he was panting then he would not eat then he started shaking so i rushed him to the vet, but he was not having one thank goodness. I wish I could not let him get the shots but I worry he will get rabies or something.