Good post - thank you.  I almost lost Rocco about 20 minutes after he had a Lepto vaccination when he was 5 months old.  He went limp, and was vomiting, had diarrhea, and was unable to stand.  My vet's office is about 4 minutes from my home so I rushed  him back, and he got a Benadryl injection to stop the reaction.  Little did I know, this is not an uncommong thing for a Lepto vac in small dogs. 
