It is often used when they are in active labor to increase contractions. Do I think harmful.. That's hard to answer. No if she is in active labor and used right. It has been my experience that using it before the first pup or before pushing can speed it up to much and it doesn't give the puppies to line things up. Sometimes that 12 hours of light contractions are needed to get the pups and body ready. That's only my opinion from what I have seen from breeding myself.
__________________ Melissa 
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