[Ellie May]

I think a big part of it is trusting that what the vet is prescribing is working well in your area of the country.

None of them are 100% effective. However, the info from the FDA about reactions and all the reports online about vet offices not carrying it anymore because of lack of effectiveness against heartworms does concern me. I won't use it for my own dog (unless she reacted to most everything else), nor do I suggest it for my family's dogs. Ellie's vet also does not go to this drug unless an owner wants to use it.

There are just older, more trusted drugs with potentially better track records. Of course in the near future when the MP3 strain will likely spread, more people will be switching to Advantage Multi (my guess anyway).

Do what you're vet is comfortable with and take my ramblings with a grain of salt. What I do or what Ellie's vet does may or may not be right. lol