I would just make sure Izzy can't really hurt her. After awhile Luna will get bigger and will be able to give as good as she gets. It took awhile but my cat finally got the dogs to understand who really runs this house.
The only one who is still brave enough to tangle with her is Moshe. You will see Herra (the cat) go by. Soon Moshe will run by in hot pursuit. I'll hear a hiss and then he will come running back crying but no worse for ware.
It's not funny and I should not laugh, but sometimes he kinda deserves it