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Originally Posted by 107barney  The article cited by KJC was" The diagnostic approach to asymptomatic dogs with elevated liver enzyme activities". |
Yes, this is one of 3 articles I refered to in providing proof for my prior statements in this thread concerning Elevated Liver enzymes, Lepto and vaccines in general, etc.
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Originally Posted by 107barney I disagree with KJC's inferences and conclusions overall.. |
No problem... Friends are not expected to see eye to eye on everything...
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Originally Posted by 107barney I also wanted to point out that the article above DOES NOT mention the word "leptospirosis" one time.. |
You are right, that specific article does not mention Lepto, but it does mention drugs, and toxins. From:
The diagnostic approach to asymptomatic dogs with elevated liver enzyme activities - Veterinary Medicine
Pertinent historical information
includes the administration of any potentially hepatotoxic drugs, supplements, or nutraceuticals; exposure to any environmental toxins or infectious agents; recent anesthetic events; ...
I am assuming vaccines, including Lepto, are included in at least one of these above mentioned categories that
can have an effect on elevating liver enzymes.
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Originally Posted by 107barney KJC research is good, but it is not going to fix your or others' dogs. Yes the liver regenerates itself, but not in the face of structure abnormalities like a liver shunt. It's like putting a piece of plastic over your house when your roof blew off. You have to fix the roof, and there is no way around it. |
I don't get this at all... do you think I think research can 'fix' mine or others dogs? Vets fix dogs. Research helps me to understand what is going on with my dog, and I try to help others understand what may be going on with their dogs, using the information they provide in their posts, and research, and some by my own personal experience. Hopefully this allows me and others to have more meaningful discussions with our vets, and to make better informed decisions regarding the heath care of our pets.
I'm almost positive Tink's liver regenerates all the time. I believe she has enough good, functioning liver to keep her asymptomatic for the most part. No, I agree it will not repair the liver shunt... if that did happen there would never be a Liver shunt or the need for surgery. Hmmmm.... I'll be looking into stem cell therapy next.... that might help!
Also, when she ate the rancid grease, this caused her ALT to skyrocket to 400, then a month later to 800. This number is directly proportional to the number of damaged hepatocytes, or in my vet's words...death of liver cells. I would think if these hepatocytes had not been regenerated by her 'available' liver, she would not have returned to her 'normal' state, or as she was before the grease ingestion event occured.
This is from the University of Tennessee, about what the liver does after the shunt is 'fixed':
Portosystemic Shunts FAQ
The liver will begin to grow as the shunt closes, and will often be normal sized in 2-4 months.