Signs of pyometra appear one to two months after the heat period. A bitch with pyometra appears depressed and lethargic, may refuse to eat, drinks a great deal of water and urinates frequently. Vomiting and diarrhea also can occur. Her temperature may be normal or even below normal. Suspect pyometra in any intact bitch that appears ill without obvious cause.
Pyometra is a life-threatening infection of the uterus that occurs most often in intact females over six years of age. The disease begins with a condition called cystic endometrial hyperplasia.
In cystic endometrial hyperplasia, the inner glandular layer of the uterus becomes thickened, fills with fluid and forms spaces like those in Swiss cheese. These endometrial changes are caused by the sustained effect of high levels of progesterone that occur during the 8 to 10 weeks of diestrus. Cystic endometrial hyperplasia provides ideal conditions for bacterial growth. The bacteria gain access to the uterus when the cervix is relaxed during estrus. The subsequent infection leads to pyometra.
Although estrogen does not cause cystic endometrial hyperplasia, it does increase the effects of progesterone, Estrogen given in the form of a mismate shot to prevent unwanted pregnancy has been associated with a greatly increased risk of pyometra and is no longer recommended for that purpose.
There are two types of pyometra: open and closed. I can explain the two if you need it.
I have more information on this if you would like, but my advice now would be to take her to a Vet. ASAP. Please keep us updated on this baby. |