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Old 11-28-2010, 03:50 PM   #1
gemy
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Join Date: Oct 2009
Location: Huntsville,Ont,Canaada
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Default Canine Hyperuricosuria

Hperuricosuria means elevated levels of uric acid in the urine. This trait predisposes dogs to form stones in their bladders of sometimes kidneys. These stones often must be removed surically and can be difficult to treat. Hyperusicosuria is inherited as as simple autosomal recesssive trait. A mutation in exon 5 of the gene Sofute carrier family 2 member 9 has been found to be associated with hyperuricosuria in dogs. A DNA test for this specific mutation can determin if dogs are normal or if they carry one or two copies of the mutation. |Dogs that carry two copies of the mutation will be affected and susceptible to develop bladder/kidney stones.

UC Davis offers testing kits. It is I believe around $60 per test.

UC Davis recommends testing any dog that has formed kidney or bladder stones comprised of urate or uric acid

I was at a breeding seminar for BRT's where we had a lecture about this condition. The lecturer shared that for Dalmations in Canada and the USA, this condition is rife, in fact so much so, that there are very few if any dogs not affected, so they are now looking to Europe in hopes of finding clear dogs.

This is a painfull condition and oftentimes affects males more than females.
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