Lady was diagnosed with KCS several years ago. She gets Tacrolimus twice a day. Optimmune didn't work for her. I also put Genteal Severe Eye gel in her eyes 4-6 times a day per her opthamologist.
I'd suggest you get a referral to an ophthalmologist at some point. Dogs with KCS are prone to other eye problems like corneal ulcers, uveitis and infections. Tear stimulators like Cyclosporin and Tacrolimus actually encourage infections as they are immune suppressants.
Neo-Poly-Dex is actually an anti-inflammatory antibiotic so KaCee must have had something else going on - an ulcer, maybe? They are very common when a dog is first diagnosed. You will only use it for a week or so.
Here is a great article on KCS:
KCS (Dry Eye)