I use the chicken flavored pill pockets made by the Greenies people. You can find them at any pet store. They really help us, because Darcy takes a lasik and 1/4 of a proin tablet 2x per day. You just drop the pill/pills in, pinch it closed, and she accepts it with no reservations.
In a pinch, we have used a bit of cheese, or peanut butter, but she will run off and lick or eat around the pill. The pill pocket is the only thing we have found to make it work.
Of course, then Baxter and Cooper eat a wellness cookie at this time as their "medicine" They do not like being excluded!