OP:
I think somebody answered your question. It is a test to show how the liver is functioning. If it is not functioning properly, drug reactions are very possible.
Since the first two reactions were just some lethargy and bumps, that would not have been a good enough reason to skip reasons. Now there is a good enough reason if you and your vet choose to. I think in general people don't understand just how dangerous rabies is (or maybe it's just that they think it couldn't possibly happen to their animal). I know I was one of those people until recently when I where the point got acroos to me realllllllly clearly. The virus is not uncommon and not only is the pet's family at risk by skipping it, so is the vet staff. And that is not fair to them. There needs to be a very good reason to go without it. And it isn't just a bite that you have to be concerned with as LadyJane said. It can happen from just a cut in the skin. Or it can happen if the saliva touches mucous membranes. And I imagine direct comtact (animal to animal) would not be necessary. It's definitely nothing to mess around with.
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