For Leptospirosis, there are currently many different vaccines available on the market for a wide variety of species and serovars. The ones currently available for dogs are chemically inactivated (killed) whole culture vaccine, which unfortunately, make them much more likely to cause vaccine reactions as opposed to most viral vaccines. Leptospiral vaccines are blamed for many of the vaccine reactions we see in dogs.
Some researches suspect that the added cellular debris and other extraneous material that find its way into leptospirosis vaccines might also account for the frequency of the vaccination reactions.
Leptospirosis is not considered a core vaccination by the AAHA because of these anaphylactic reactions.
As with any vaccine, certain groups of pups are especially at risk for reaction; such as yorkies. Vaccination of ones' pups is a decision which should be based on the area one lives, the risk of infection in that area, vaccination-based reactions, and the risk of unvaccinated infections.
Current researchers as studying the link between lepto, and chronic kidney and liver disease. Like any infection, lepto invades these two organs, and the toxins it produces damages their functionality.
In the 2007 Michigan study 25% of the unvaccinated healthy dogs showed antibodies to the disease which implies that infection had occurred prior, without the owners knowledge. CIN, Chronic kidney inflammation /Chronic Interstitial Nephritis is the leading cause of kidney failure in dogs, and CIN is often seen as the result of leptospirosis infection. Liver disease is also being studied further in connection with leptospirosis toxicity.
Hope this gives you some added information..... |