If your traveling on a flight that has the little tv's on the back of each seat let the stewards know you are travling with a pet. Normally the tv equiptment is kept under the floor of the middle seat and it gets very warm and can be dehydrating. I always travel with an extra blanket, baby wipes and pee pee pads. Be prepared for a layover with carry on food and treats and a little bowl for water.
Have a wonderful trip!!