I use the frontline plus as well, and my location I have to apply it every 4 weeks. So far the only one that reacts is the cat, he gets a little mellow for the first day, and sometimes pukes, but I apply it to the back of his head (the one spot he cant groom). In addition, because my puppy gets to go outside I have to have a flea collar on him until October (yikes, he hates it!) and every week I bathe him with a flea solution. But considering my indoors only cat (really, never went outside once and at the time it was just him and I in the house) somehow got fleas in March before I thought flea season would start I can tell you it is awful here for fleas. Probably because of all of the strays. And as it turns out, my cat is allergic to fleas, so after just a week I noticed him scratching at himself and saw he had a horrible rash and his fur was falling out. It was a painful process clearing my house of fleas but now we are flea free and with the frontlines help (i think so anyway) I havent seen a sign of flea or tick on either one. |