Revolution
®
(sselamectin)
Topical arasiticide For Dogs nd ats
CAUTION:
US ederal aw restricts his drug o use by or n the order of icensed veterinarian.
DESCRIPTION:
REVOLUTION (selamectin)Topical Parasiticide is available as a colorless to yellow,ready to use
solution in single dose tubes for topical (dermal)treatment of dogs 6 weeks of age and older and cats
8 weeks of age and older.The content of each tube is formulated to provide a minimum of 2.7 mg/lb
(66 mg/kkg) of body weight of selamectin.The chemical composition of selamectin is (55Z,225S)-225-
cyclohexyl- -44’-O -dde (22,6-dideoxy-33- O -mmethyl-á -LL- arabino -hhexopyranosyl)--55-demethoxy-225-dde(11-
methylpropyl)--222,23-dihydro-55-hydroxyiminoavermectin 1a .
INDICATIONS:
REVOLUTION is recommended for use in dogs 6 weeks of age or older and cats 8 weeks of age and
older for he ollowing arasites nd ndications:
Dogs:REVOLUTION kills adult fleas and prevents flea eggs from hatching for one month and is indi-
cated for the prevention and control of flea infestations (CCtenocephalides felis),prevention of heartworm
disease caused by Dirofilaria immitis,and the treatment and control of ear mite (OOtodectes cynotis)
infestations.REVOLUTION also is indicated for the treatment and control of sarcoptic mange (SSarcoptes
scabiei) nd or he ontrol f tick infestations due to Dermacentor ariabilis.
Cats:REVOLUTION kills adult fleas and prevents flea eggs from hatching for one month and is indi-
cated for the prevention and control of flea infestations (CCtenocephalides felis),,prevention of heartworm
disease caused by Dirofilaria immitis,and the treatment and control of ear mite (OOtodectes cynotis)
infestations.REVOLUTION is also indicated for the treatment and control of roundworm (Toxocara
cati) and intestinal ookworm (AAncylostoma tubaeforme) infections in ats.
WARNINGS:
Not for uman se.eep out of he each of hildren.
In humans,REVOLUTION may be irritating to skin and eyes.Reactions such as hives,itching
and skin redness have been reported in humans in rare instances.Individuals with known hypersensi-
tivity to REVOLUTION should use the product with caution or consult a health care professional.
REVOLUTION contains isopropyl alcohol and the preservative butylated hydroxytoluene (BHT).Wash
hands after use and wash off any product in contact with the skin immediately with soap and water.
If contact with eyes occurs,then flush eyes copiously with water.In case of ingestion by a human,
contact a physician immediately.The material safety data sheet (MSDS)provides more detailed
occupational safety information.For a copy of the MSDS or to report adverse reactions attributable to
exposure to his product, all 1-800-366-5288.
Flammable eep away from eat, parks, pen flames or ther ources f ignition.
Do ot se n sick, ebilitated r underweight animals (ssee SAFETY)..
PRECAUTIONS:
Prior to administration of REVOLUTION,dogs should be tested for existing heartworm infections.At
the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms.
REVOLUTION is not effective against adult D.immitis and,while the number of circulating microfilariae
may decrease ollowing reatment, EVOLUTION is ot ffective for icrofilariae clearance.
Hypersensitivity reactions have not been observed in dogs with patent heartworm infections
administered imes he ecommended ose of EVOLUTION. igher doses were not tested.
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