I've always used Advantix and it works well for us.
Neither one of my boys have had ticks or fleas.
To
Ellie May: What is permethrin?
(Perhaps I should do some googling.

)
The only thing I do not like about Advantix is that it is highly toxic to cats, and I have a cat, so I have to keep them separated for a few hours.
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♪ Jimi | Marshall | Hendrix ♫
"When the power of love overcomes the love of power, the world shall know peace." - Hendrix