Oh yes. I rehomed Cooper at 16 weeks and she was HORRIBLE at biting all the time when playing, and she bit *hard*
This was due to the fact she was taken from her litter wwaayyyyy to early at 5-6 weeks. She has also had many other "issues" I feel came from this mistake of letting her go too early.
I did as you have been advised above. I would not let her use me as a chew toy and would often yelp, usually b/c it did hurt.
She quickly learned this was not acceptable. Good Luck to you. You must be consisten and patient.