My sister has a Great Dane that I don't completely trust around my kids or my Yorkie. In his case though, he was never around small kids when he was young. When he was about 7 or so, he bit my daughter (also about 7 years old). He didn't sink teeth in but rather lunged and scratched her face with his tooth. He has lunged at other kids too. Now they have a daughter and he is very protective of her. Just doesn't like other kids or other people's small dogs. I fully suspect it has a lot to do with what they are raised around.
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~ Angie |