Which one do you prefer?
It says to start them on it 2-4 weeks prior to their heat cycle.

How do I know 4 weeks before their cycle?
Does it help to regulate their cycles? I have one girl that it has been 9 months since the start or her last heat. The other two girls that all 3 were in heat the same time last time, have already had their heat again and this one is not showing any signs.