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Originally Posted by dwerten  so has your dog had this since a pup? As demodex is from the mother dog and usually if they have this it is from the time they were a pup - it usually does not creep up later - it starts with a small spot and it is usually moist and stinky. It is due to the immune system being poor. This is a tough one to get rid of  Many dogs have had great success with promeris but some get sick from it per our dermatologist. My friends dog has had this since a pup and she has had a horrible time of it but i have heard of many using promeris and it working real well. Usually they use ivermectin and that drug is very strong - make sure to have bile acids done along with cbc panel. Our vet made us do this before using atopica. NEVER EVER MIX IVERMECTIN AND KETOCONAZOLE - a dermatologist gave my friends dog this and she went into a coma and almost died those drugs SHOULD NEVER BE MIXED EVER - the ketoconazole breaks the blood barrier wall allowing the ivermectin to go to the brain and seizure then coma. I would not use a shampoo nor an internal ketoconazole on my dog taking this. Even if a shampoo it goes into the blood stream through the skin so please be careful as this dermatologist who has practiced for 20 plus years SCREWED UP BIG TIME and she apologized to my friend over and over and it was a 3,000 vet bill to save my friends dog.
if your dog walks in a drunken stupor AT ALL on this drug STOP IMMEDIATELY !!!! that is a sign of ivermectin toxicity. This drug is off label it is not approved by fda in dogs. I do not mean to scare you but you need to pay attention. My friends dog has been on a low dose of this stuff for years under one dermatologist but when she did not want to drive as far to my dermatologist she went to another one close to her that has practiced even longer than mine who is CONSERVATIVE and then this happened so she is back with mine and her dog is now on a daily small dose of interceptor as it has a different type of drug like ivermectin in it.
I just want to share this all with you as I would hate to not say anything and something happen to your dog as again my friends dog has been fine on it for years but demodex can be a nightmare to get rid of
here is what happens is the immune system is poor and every dog and human has mites on skin but when immune system is poor the mites take over and get out of balance and you get skin issues.
here is some info Multiple oral dosing of ketoconazole increases dog exposure to ivermectin Red, Puppy, & Follicular Mange (Demodectic, Demodex) in Dogs Demodectic Mange & the Immune System in Dogs |
Your wrong about dogs only getting mange as pups. My dog had it at 1 1/2 yrs old. My vet said all dogs have mites when a dogs imune system gets down they can multiply and cause mange