I have a Yorkie and a hundred pound clumsy Weimaraner, in my situation they get along great, but from early on my Weimaraner showed no interest in wanting to play with the Yorkie, it's as if she's just too small for him to have any fun with. She also learned to stay out of the big dog's way so she didn't get stepped on. They do cuddle up and sleep together so I know they love each other