My two puppies just chewed a hole in my Anne Klein shoes.

I don't care so much, though about the shoes though I know it's a bad behavior I also know that they will stop soon. Their mother chewed everything in sight when she was a puppy and she's almost 3 now and doesn't destroy anything and hasn't for some time.
If you can't watch your puppy you should put her in an X-pen with some toys to chew on. That'll keep her safe and away from stuff to chew that you don't want her ruining.

Good luck.