Hi, Here are the instructions, although I also save just a few drops to add to the back rump area! I call it the backdoor protection..
Do not bathe your dog three days before or three days after applying Frontline Top Spot. ... INSTRUCTIONS:
To Remove applicator from child-resistant package. Use scissors. Or lift and remove plastic tab to expose foil, then peel down. To Open applicator. Hold applicator upright and snap applicator tip away from face and body. To Apply FRONTLINE Plus. Place applicator tip through animal's hair to the skin level between the shoulder blades. Squeeze applicator, applying entire contents in a single spot to the animal's skin.
here is the link
http://frontline.au.merial.com/faq/dogs/index.asp