I got this advice from my pediatrician when my kids were little, but I think it can apply to dogs too.  DO NOT make a huge deal of your leaving, calmly say Mommy will see you soon, give a kiss and a cuddle.  Children and animals feed off of our emotions, so if you're upset, they get upset.  If you act like it's no big deal, it'll be okay
 
How long are you going to be away?