Quote:
Originally Posted by EnchantedToi  Interesting letter received , sharing it to help with all those interested and researching the Biewer
We have received your inquiry about Biewer Terriers.
For the detection of mixed-breed dogs, we are currently able to detect signatures of 153 American Kennel Club (AKC) defined breeds and 4 non-AKC breeds. We are working towards expanding this to the full list of AKC registered breeds and more of the popular non-AKC breeds over the next year. Unfortunately, since the Biewer Terrier is not a breed we currently recognize, it will not be included in this expansion of our test.
The analysis is designed to find matches to the breeds in our database, so if the computer can find matches between your dog's DNA and our designated breeds with enough confidence, it will identify them. If your dog does contain a portion of Biewer Terrier, the analysis may identify Minors of breeds that are genetically closely related to it.
However, if the computer cannot find breeds that match with enough confidence, the Biewer Terrier portion will be left blank or it will be considered "too mixed" to call. For the other breeds in your dog, if there is a significant component from a breed that is covered in the test (e.g., a purebred dog in last three generations) then Wisdom Panel MX should be able to detect these other breeds. Overall, it is important to note that the presence of a breed signature that the test does not detect at present may cause inaccuracies in the analysis.
In regards to your purebreed inquiry; Wisdom Panel MX test analyzes over 300 genetic markers to determine the ancestral breed composition of a mixed-breed dog. Within this panel, there are almost no markers which are absolutely specific to one breed. Each breed will have a combination of markers within the panel that represent the breed. Within a mixed-breed dog, depending on the heritage of the breeds, not all of those markers may be passed down through the generations to appear in the genetic make-up of the dog that is tested. For example, on average, you would only expect 25% of the breed markers from a Grandparent to be passed down to the current dog. Thus, the way the test works is to use a best-fit model that is selected on the basis of the highest probability for each breed depending upon the analysis of markers that are found in the current dog. The final report is generated depending on the highest probability breeds found with a lower limit cut-off to ensure that the false positive reports are reduced to a minimum.
The relationship between the markers and breeds is unfortunately proprietary information as it forms the basis of the test and is therefore not publicized. Where pure breed dogs are concerned, most often the report generated by the test will simply indicate the pure strain of the breed in question as no other markers will be found at a high enough confidence level to generate a result. However, although our sample base covers 157 breeds and comprises more than 8,700 samples in total, there are several cases in which pure breed dogs may not be detected as purebred by Wisdom Panel MX test.
First, if the dog in question is not or was not bred within the continental US, even if it is an example of an AKC recognized breed, then we may not pick up the breed signature as the distinctive markers that identify the breed may vary greatly in foreign lines. Secondly, if there has been a very isolated breeding line for the pure breed, then we may not have enough coverage of that breed's gene pool to identify the dog as purebred. For these reasons, we do not advertise or recommend the use of Wisdom Panel MX as a test for confirming the purity of a purebred dog. This is due to the fact that Wisdom Panel MX is designed to find multiple breeds in an analysis, under the assumption that the dog it is testing has more than one breed in its mix. A test to determine breed purity would need to be designed for that purpose and its accuracy validated.
We hope this answers your inquiry. If you have any additional questions, please do not hesitate to contact us at customercare@marsveterinary.com or 888-K9 PET TEST (1-888-597-3883).
Regards,
Mars Veterinary
Customer Care Department Dog DNA Test | Mixed Breed Analysis | Canine Breed Testing |
Funny how some people can read the same thing as see totally different things. To me, this is very clear.
The MARS people are stating that their test was developed
"FOR THE DETECTION OF MIXED BREED DOGS". To determine the makeup of these dogs, the tests uses DNA from 153 AKC defined breeds and 4 non- AKC breeds. (not yet all AKC breeds - NOTE
*"THE BIEWER TERRIER IS NOT A BREED WE CURRENTLY RECOGNIZE, it will not be included in the test)
The test finds matches in the database to these samples and identifies them. If there are significant components from a breed that is covered (e.g. a purebred dog in last three generations), the Wisdom Panel should detect theese other breeds. *
"OVERALL, IT IS IMPORTANT TO NOTE THAT THE PRESENCE OF A BREED SIGNATURE THAT THE TEST DOES NOT DETECT AT PRESENT MAY CAUSE INACCURACIES IN THE ANALYSIS"
"Where pure breed dogs are concerned, most often the report generated by the test will simply indicate the pure strain of the breed in question as no other markers will be found at a high enough confident level to generate a result. HOWEVER, although our sample base comvers 157 breeds and comprises more than 8,700 saples in total,
THERE ARE SEVERAL CASES IN WHICH PURE BREED DOGS MAY NOT BE DETECTED AS PUREBRED BY WISDOM PANEL MX TEST.
1)
IF THE DOG IN QUESTION IS NOT OR WAS NOT BRED WITHIN THE CONTINENTAL U.S. even if it is an exaqmple of an AKC recongnized breed, THEN WE MAY NOT PICK UP THE BREED SIGNATURE AS THE DISTINCTIVE MARKERS THAT IDENTIFY THE BREED MAY VARY GREATLY IN FOREIGN LINES.
2)
IF THERE HAS BEEN A VERY ISOLATED BREEDING LINE FOR THE PURE BREED, THEN WE MAY NOT HAVE ENOUGH COVERAGE OF THAT BREED'S GENE POOL TO IDENTIFY THE DOGA AS PUREBRED. FOR THESE REASONS, WE DO NOT ADVERTISE OR RECOMMEND THE USE OF WISDOM PANEL MX AS A TEST FOR CONFIRMING THE PURITY OF A PUREBRED DOG. .... A TEST TO DETERMINE BREED PURITY WOULD NEED TO BE DESIGNED FOR THAT PURPOSE AND ITS ACCURACY VALIDATED.
I don't see anything hard to understand in these statements.. they are saying clearly that the test you have been using to prove that the Biewer is not a purebred dog IS NOT or WAS not made for that purpose, nor is it accurate for that purpose. (No matter how loudly you say it, it still doesn't work .. you are using an invalid measure to try and prove something you want to prove.)
There are two VALID reasons why you may have gotten the results you did.. we know that these dogs were not bred in the US and we KNOW that it was a very limited, isulated breeding pool from which to draw. This makes perfect sence.
I'm sorry for making this SUCH a big deal and I'm sorry for getting so passionate about this ... But is IS a big Deal.. People are trying to high jack an entire breed.. sell them down the river.. say they are something they are not JUST so they can get AKC acceptance ??? Is it worth it ???
We will get there, but we will do it the RIGHT way. There is no need to deceive, falsify or twist .. these dogs deserve nothing less. We don't need to go in the back door.
-Diana
