We gave our litter of puppies a bath at five weeks (last week) only becuz they reeked of pee from playing all over the newspaper they were peeing on. They shook the whole time and did not like it, especially when I got out the hair dryer! I think I should have waited a few more weeks, but it is hard to kiss on puppies when they smell like little urinals. hehe. However I will try to hold off on another bath till ABSOLUTELY NECESSARY. Btw, this is our first litter, so we are making all the mistakes now. Poor little puppies...