It will definitly be an adjustment. We moved 3 1/2hrs away about 7yrs ago. I don't think the pups had any trouble adjusting. I had a silky terrior at the time who was very emotional. He did great.
I would do little trials on leaving her alone. Like sit ouside for ten minute intervals to see what she does and slowly increase it.
Just remember to take her to the place you want her to potty first. That is really important. I remember reading something on that.
Good luck with your move