We have a 20lb cat and Sophie, who is 8lbs. The cat is older, about 14, and Sophie is 7 1/2. We were worried that Mr. Kitty would be aggressive toward Sophie when she was a little puppy, but actually, it is Sophie who is aggressive toward Mr. Kitty. He is very gentle and has never shown aggression, but Sophie "herds" Mr. Kitty and is also a tattle tale. She also attacks him if we touch him (very jealous). We also notice that they do like each other and play at times. Kitty just "puts up" with Sophie. It is a very strange relationship.