When you're using it to bake, there is no difference. I just made 2 batches of cookies, the first batch were with margarine, as I had some to finish up, the 2nd batch was with butter, there is no flavor what so ever in the flavor of the cookies...Also, I have always bought 5-6 boxes of margarine/butter at a time and frozen it, it never took away the flavor of the margarine. I would still be using margarine now, if son in law wouldn't have told me some stuff on margarine. He said if you leave it out and there are flies out, they won't even come near it. something to do with plastic..