I encountered the same problem. A few days before her scheduled surgery, Sasha went into heat. If your little one is normally wild and crazy and now she seems wiped out all the time, that's completely normal. When females go into heat, that is one of the symptoms that they can experience. It didn't really take much effect on mine. She just got swollen more than anything, but didn't really change her activeness at all. Hang in there! She'll do just fine!