Bile acids can be up if the liver is not functioning properly.
She could've gotten into something very toxic but I think you would've known about it. Had she had any meds or vaccines in the last week or two?
The next step does depend on the numbers but most likely it will be a Protein C test or scintography or the vet will try to talk you into an ultrasound.
Is she having any symptoms?
Lethargy, depression, inappetance, gastrointestinal issues, drooling, circling, head pressing, seizures?
Liver disease is scary but it isn't a death sentence.
And after all of this is figured out, she can still be spayed.