Thanks for the reply. I think she was shaking because she was afraid of me. That was what was really scaring me. She ate really well earlier and drank water and right now she's trying to take her kitty toy out of her carrier. She's still a bit skittish, but she's doing better. I boiled some more chicken to see if she'll take it. It was just a big scare. She had never reacted this way with her other 2 vaccines, and since I had read about the Lepto I was really worried. But she slept the whole afternoon and part of the night and now she's playing, so I'm able to breathe a little easier. Thanks again for the advice.