Quote:
Originally Posted by Ladymom  Ivermectin is the main ingredient in Heartguard. The warning is that there may be a reaction if you use Heartguard and the new Comfortis for fleas together. |
The FDA actually warns that it has received reports of adverse reactions in dogs receiving the drug
Comfortis® (spinosad) concurrently with
high, extra-label doses of the drug ivermectin. The clinical signs of these adverse reactions are consistent with ivermectin toxicity.
My concerns were with my Vet not knowing about these warnings since Bella was given a single dose of Ivermectin. Ivermectin is used to treat mites or mange. The Vet quoted that the small amount of Ivermectin in Heartguard should not be a problem while using Comfortis. I'm not sure though I would want to chance it?