Okay this is what you want to do mix your self up some oxy clean with hot water . go by your self one of those little green machines.. you want to take it out not cover it up.. so Take you hot oxy clean mixture and spray it on the spots not sloppy heavy but make sure it is going in to the matteress.. let it stand and take your little green machine in suck up the old pee and oxy clean solution .. leave it air dry till dry ... smell and check if still there do the process again.. just make sure it drys good put a fan or leave window open.. do it early morning so that it has all day to dry.. after that spray the whole matteress with OUST love that stuff.. should be good to go .. I would tell you to do it on carpet like that to.. but when i became a yorkie mom got rid of carpet put hardwood floors all in my house... Good Luck