[BamaFan121s]

Breeds that have already been established have their own breed specific issues--not just genetic, but physical as well. Breeders of a specific breed can identify them and control them. When you cross two breeds, you have then have offspring that will be succeptable to complications from TWO gene pools. You may luck up and produce a dog that has the 'best of both worlds' but you may get one that has the worst of both.
The problem is, this doesn't often seem to be taken into consideration. I have yet to see, either on this forum or elsewhere, the precautions taken to prevent these types of issues. Or any long term study proving or disproving the theory.
Seems like an awful lot of "theory" to be playing around with. These issues are not being taken into account and nothing seems to be done to prevent them, predict them or even keep track of them.

And again, there still seems to be one major thing lacking--the purpose. Other than to produce what suits the immediate desire, with one generation.