I have a Staffordshire Bull Terrier with my little 3lb yorkie...My Staffy lived with a yorkie before...luckily he is gentle and obedient, he is very good with her, I just make sure he is not allowed to get too excitable around her (jumping up etc) It works out very well with them both..but i wouldn't say that they play together much..but then my staffy is now 8 years old so maybe not as playful as when he was younger.