Advantage Multi is just too new for me to like and I don't like over the shoulder heartworm preventatives. If you HAVE to have something for mosquitos or ticks, you could go with K9 Advantix but if you can get away with just treating for fleas, I'd go with regular Advantage (if you have to use anything at all). You can also use Frontline for just fleas and it may repel some ticks.
I like Interceptor, Sentinel and sometimes Heartgard for heartworms.
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