This is not fair to you or your family. It is a difficult situation to be in, I understand.
Could the kids go outside in the backyard to play? If they are this out of control, then seriously, you do not need to put up with it. It's your house and family that are at stake. the mom has little control over the children, which is sad. they are little. wait until they are older..... it will be worse.
tell the 22 yr. old that your unable to have her over anymore because it is too stressful on you and your family. I think that sometimes othes do not realise that they are being intrusive.