Interceptor, advantage, frontline, etc.....are all chemicals. I'd definitely wash it off her and wouldn't use it on her again.
I haven't ever had any reaction in mine with frontline, but my cat had a reaction to promeris.
For my dogs I have never applied the full applicator....it's for dogs up to 22 pounds...and mine weigh half that or less.
__________________ Deb, Reese, Reggie, Frazier, Libby, Sidney, & Bodie |