Mia doesn't like car rides at all. She will pant the entire time, so we just went on vacation and took her with us and my vet gave me a sedative and it works really good. Make sure you give what the vet prescribed,(not a bit more) because it does make them drowsy. Mine did very good and wore off in about 4 hours. We gave it to her when we left and when we came back. She was still awake enough that when we stopped for a pee break, she did go. Just make sure you keep a close eye on your baby, because there is no way she could defend herself against anyone or any animal. Hope this helps you.. It deffinatley will keep the stress level down on both of you during the ride.