Spay day is sooo miserable.
She does NOT need to wear the e-collar for two weeks straight.
It can come off when the animal is supervised.
I prefer not using it and using a onesie instead.
Some dogs still pick at their stitches through it though, so it doesn't work for everyone. It's worth a try.
She probably won't have a bowel movement til a day or maybe even two after surgery. She will probably urinate tonight or tomorrow morning. If you mean when can you take her out to play, I wouldn't until the stitches come out.
No jumping or running for 7-10 days...