Oh my gosh.... that first work day is KILLER (for us).
You've already gotten good advice. It's so hard, but try not to be too emotional at the leaving time. You want your puppy to learn that it is TOTALLY NORMAL for you to leave.
Small crates worked better for us as they have to settle right down as there is no room for anything else. And just be consistent. Our older dog has the run of the house, but Coby is still crated whenever we leave. When we put on our shoes and coats, without a word, he simply runs into his kennel and waits for his treat (there's still a treat for him every time). The last couple of weeks, when I put my lip gloss on, he runs in his kennel.
Good luck. It's so hard at first.