From what I  understand, you do need to use it with caution.  I have never used it but I have just read that it can cause heart arrythmia.  No, the dose is not the same for a Yorkie as a Great Dane, from what I understand.   
Calcium works on muscle and the heart is a muscle that is very influenced by calcium.     
Since there does seem to be some issues with it, I would do a ton of research on it before I used it.     |