My vet recommended only one shot at a time and never anything combined, but would wait at least two weeks in-between vaccines.
Boosters for Rabies and Distemper are only every three years. My vet also reduces the amount of the vaccine they are given as the minimum dose mandated is for a much larger dog.
Paula - interesting that your vet doesn't recommend Lepto. When I questioned my vet about it, she said we have 6 very active strains of Lepto in MI and if your pup is outside for pottying/walks or does play dates, it is an important vaccine.....
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