I currentlly have a 90 lb. lab who lives inside, very nicely with my little ones... She is VERY cautious when playing and will not run when Hope is near her. She knows when to be cautious, and Hope can eat her "droppings" under her feet when they eat...
I truly beleive it depends on the larger pup's temperment and upbringing. My big girl was raised with the little ones and really has no idea that she is so big. I also think that their temperment around small children will tell alot about how they react to smaller pups. My big girl, Laci, is the sweetest, most tolerant thing ever but they are NEVER left alone...
Good luck
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