Most of my life has been spent with male dogs. Over the last 15 years, I have had two females. Both of the girls were real, well ... *bitches* when it came to young children or animals

. They had no tolerance whatsoever. Da BOYS, however, have always been patient with young'uns of all species.
My daughter is staying with us for a while, and she has a 90# pit ... he's the sweetest thing in the world when playing with the pup, up to allowing the pup to swing from his cheeks (which I stop as soon as I see it). When he's had enough, he hops up on a bed or some place out of reach. When he's asleep on his bed and the pup comes carousing in, he grumbles and makes all kinds of noises - but when the pup leaves, Nitro's head pops up and he looks around as if to say: HEY! Where'd da kid go???
In my experience, males (all of mine have been neutered) are far more accepting of puppies than females. The girls eventually "come around", or at least learn to tolerate a new family member, but the boys accept them on sight.
Your girl will more than likely come around. I've had the pup for a month now, and Katie has finally stopped snarling at him every time he comes within 4 feet of her. She still doesn't
like him, but she has conceded that he can breathe the same air she does