I personally have found that there is indeed a difference between the two. as far as personality,a boy is usually more playful than a girl, if she is energetic he is more energetic.boys love you with lots of affection but the girls are more laid back and will cuddle next to you. they follow you more than the boys do. all you have to do when looking is observe the differences when you go to pick your pup,play with each one and you will see the slight differences.you will also have to pay attention to sex of litter as far as girl to boy ratio. if there are more girls in the litter the boy will be more calm and laid back, and if you are getting a girl out of an mostly male litter the girl will be more aggressive like the boys.and not to mention mom and dads temperment