Rocco was throwing up in the car ALL THE TIME when I first got him. Drove me crazy. He would throw up like 4-7 times each car drive depending on the distance. I noticed he would throw up more when I drove through the streets because of the stop and go, as opposed to the freeway. I just kept putting him in the car until it eventually stopped at 10 months, YES 10 MONTHS..lol..Now he will still get car sick if I'm driving too long with too much stop and go but he's better for the most part. Just keep taking them for car rides and carry lots of paper towels